AGRL2-4 GAIN subdomain A

Definition

This entry describes the GAIN subdomain A primarily found in adhesion G protein-coupled receptors L2-4 (AGRL2-4). It is also found in Latrophilin/CIRL, CELR1, AGRB1-3 and related G-protein -coupled receptors (GPCR). The GAIN domain consists of an N-terminal HormR-like domain (IPR053984), followed by the GAIN domain which consists of a stalk (consisting of subdomains A and B) and a GPS motif (IPR000203), followed by a C-terminal transmembrane region (IPR000832) PMID:22333914.

10 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (10 proteins: gene, accession, name)

• ADGRB1
• ADGRB2
• ADGRB3
• ADGRL1
• ADGRL2
• ADGRL3
• ADGRL4
• CELSR1
• CELSR2
• CELSR3