FAST kinase-like protein, subdomain 1

Definition

This family represents a conserved region of eukaryotic Fas-activated serine/threonine (FAST) kinases ([ec:2.7.1.-]) that contains several conserved leucine residues. FAST kinase is rapidly activated during Fas-mediated apoptosis, when it phosphorylates TIA-1, a nuclear RNA-binding protein that has been implicated as an effector of apoptosis PMID:7544399. Note that many family members are hypothetical proteins. This region is often found immediately N-terminal to the FAST kinase-like protein, subdomain 2.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• FASTK
• FASTKD1
• FASTKD2
• FASTKD3
• FASTKD5
• TBRG4