Myotubularin-like phosphatase domain

Definition

This family represents the phosphatase domain within eukaryotic myotubularin-related proteins. Myotubularin is a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3,5)-bi-phosphate PMID:12847286. Mutations in gene encoding myotubularin-related proteins have been associated with disease PMID:12045210.

14 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (14 proteins: gene, accession, name)

• MTM1
• MTMR1
• MTMR10
• MTMR11
• MTMR12
• MTMR2
• MTMR3
• MTMR4
• MTMR6
• MTMR7
• MTMR8
• MTMR9
• SBF1
• SBF2