Seroatlas · Protein domains

Anoctamin, transmembrane domain

IPR049452

Definition

This entry represents the transmembrane domain from the anoctamin family of proteins, which includes anoctamin1-10 (Ano1-10 or TMEM16A-J) [[cite:PMID:18724360], [cite:PMID:25383531]]. Seven members could be divided into two subfamilies; Ca2-dependent Cl(-) channels (TMEM16A and 16B) and Ca2-dependent lipid scramblases (TMEM16C, 16D, 16F, 16G, and 16J) PMID:23532839. This entry also includes anoctamin-like protein At1g73020 from Arabidopsis and increased sodium tolerance protein 2 (Ist2) from budding yeasts.

10 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (10 proteins: gene, accession, name)

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