Small proline-rich protein 2

Definition

Small proline-rich (SPRR) proteins are structural components of the cornified cell envelope of stratified squamous epithelia. They are subdivided into three families: SPRR1, SPRR2, and SPRR3 PMID:9888996. This entry represents SPRR2, a family of small proteins rich in proline, cysteine and glutamate. They contain a tandemly repeated nonamer, PKCPEPCPP PMID:3133554. They are components of the cornified envelope of keratinocytes PMID:11279051.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• SPRR2A
• SPRR2B
• SPRR2D
• SPRR2E
• SPRR2F
• SPRR2G