Alpha/beta knot methyltransferases

Definition

This entry represents a α/β knot structural domain that can be found in many RNA methyltransferases, including members from the SPOUT superfamily, EMG1/NEP1 methyltransferases and SAM-dependent RNA methyltransferases. The α/β knot structure is extremely rare in protein structures as it poses a folding problem PMID:12596263.

7 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (7 proteins: gene, accession, name)

• EMG1
• GVINP1
• MRM1
• MRM3
• SLC15A2
• SPOUT1
• TARBP1