Acyl transferase/acyl hydrolase/lysophospholipase
IPR016035
Definition
This superfamily represents a structural domain with a 3-layer α/β/α topology. This domain can be found in acyl transferases such as bacterial malonyl-CoA ACP transacylase (FabD) and the homologous domain from eukaryotic fatty acid synthase PMID:12575934. This domain is also found in lysophospholipases such as cytosolic phospholipase A2 (which has additional structural features) PMID:10319815, and in patatin proteins, which are plant glycoproteins that act as non-specific lipid acyl hydrolases PMID:12779324.
17 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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