RAP domain
IPR013584
Definition
The ~60-residue RAP (an acronym for RNA-binding domain abundant in Apicomplexans) domain is found in various proteins in eukaryotes. It is particularly abundant in apicomplexans and might mediate a range of cellular functions through its potential interactions with RNA PMID:15501674. The RAP domain consists of multiple blocks of charged and aromatics residues and is predicted to be composed of α-helical and β-strand structures. Two predicted loop regions that are dominated by glycine and tryptophan residues are found before and after the central β-sheet PMID:15501674. Some proteins known to contain a RAP domain are listed below: Human hypothetical protein MGC5297, Mammalian FAST kinase domain-containing proteins (FASTKDs), Chlamydomonas reinhardtii chloroplastic trans-splicing factor Raa3.
6 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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