Soluble quinoprotein glucose/sorbosone dehydrogenase, beta-propeller domain superfamily
IPR011041
Definition
This superfamily represents the β-propeller domain found in dehydrogenases from all cellular organisms. Quinoproteins form a class of dehydrogenases distinct from the NAD(P)- and flavin-dependent enzymes, using one of four different quinone cofactors for the oxidation of a variety of compounds. Soluble glucose dehydrogenase (s-GDH) from the bacterium Acinetobacter calcoaceticus is a quinoprotein that requires the cofactor pyrroloquinoline quinone (PQQ) to catalyse the oxidation of glucose to gluconolactone PMID:10518528. s-GDH has six 4-stranded β-sheets in a β-propeller fold.
7 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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