Ubiquitin system component CUE

Definition

This domain promotes intramolecular monoubiquitination and has a dual role in mono- and poly-ubiquitination recognition, being involved in binding ubiquitin-conjugating enzymes (UBCs) [[cite:PMID:12573224], [cite:PMID:12628920], [cite:PMID:23665229]]. CUE domains also occur in two proteins of the IL-1 signal transduction pathway, tollip and TAB2.

10 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (10 proteins: gene, accession, name)

• AMFR
• ASCC2
• AUP1
• CUEDC1
• CUEDC2
• N4BP2
• SMARCAD1
• TAB2
• TAB3
• TOLLIP