Seroatlas · Protein domains
Anoctamin, dimerisation domain
PF16178
Definition
This entry represents the dimerisation domain of anoctamin family of proteins. Seven members can be divided into two subfamilies; Ca2-dependent Cl(-) channels (TMEM16A and 16B) and Ca2-dependent lipid scramblases (TMEM16C, 16D, 16F, 16G, and 16J). This domain is responsible for creating the homodimeric architecture of the chloride-channel proteins.
8 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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