RFPL defining motif (RDM)

Definition

The RDM domain is found on RFPL (Ret finger protein like) proteins. In humans, RFPL transcripts can be detected at the onset of neurogenesis in differentiating human embryonic stem cells, and in the developing human neocortex PMID:18656177. The RDM domain is thought to have emerged from a neofunctionalisation event. It is found N terminal to the SPRY domain ([pfam:PF00622]).

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• RFPL1
• RFPL2
• RFPL3
• RFPL4A
• RFPL4AL1