Seroatlas · Protein domains
NXPE, C-terminal
IPR057106
Definition
This domain is found at the C-terminal of NXPE and similar proteins, mainly from animals. This domain is predicted to adopt an α/β structure with similarity to hydrolase domains. Neurexophilins (NXPE) are secreted neuropeptide-like glycoproteins originally discovered as alpha-neurexin ligands and later found to bind to the LNS2 domain of alpha-neurexins. NXPE are encoded by four genes that are highly conserved in vertebrates but absent from invertebrates PMID:31566781.
6 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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