Ciliary Microtubule Associated
IPR051291
Definition
The CIMAP family proteins are associated with the structure and function of the sperm tail, specifically the outer dense fibers. These fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. The CIMAP family proteins are thought to play a role in maintaining the passive elastic structures and the elastic recoil of the sperm tail, which are crucial for sperm motility and fertility. The family is characterized by a similarity in sequence and structure across different species, suggesting a conserved function in sperm tail integrity and function.
5 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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