Immunoglobulin superfamily V-set and transmembrane domain-containing protein
IPR051102
Definition
This family of proteins includes members that are involved in various cellular processes, including immune response modulation, cell differentiation, and regulation of cell motility. Some proteins in this family function as inhibitors of T-cell proliferation and IL2 production, playing roles in immune regulation. Others are implicated in adipocyte differentiation by promoting the expression of specific transcription factors. Additionally, certain family members are involved in the negative regulation of cell motility, interacting with other proteins to influence cell migration, fusion, and morphology. Some proteins also participate in maintaining neural networks and enhancing calcium channel currents in photoreceptors, indicating a role in neural and visual functions.
8 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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