Mucin/von Willebrand/Thrombospondin superfamily
IPR050780
Definition
The protein family is involved in various biological processes, including the protection of mucosal surfaces, hemostasis, and developmental events in the central nervous system. Members of the family function as gel-forming mucins that coat epithelia, providing a protective barrier against pathogens and facilitating nutrient absorption. They also play roles in platelet adhesion during vascular injury, neuronal aggregation, and gamete recognition during fertilization. Some family members act as chaperones for other proteins, contribute to the structural integrity of specific tissues, and participate in innate immunity by storing antimicrobial molecules.
10 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
Loading the interactive Seroatlas explorer...