Peptidase C85-like

Definition

This entry represents human Deubiquitinase OTUD6B, OTU domain-containing protein 5 (OTUD5) and other C85 peptidases that contain the OTU domain ([interpro:IPR003323]). OTUD6B may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1 [[cite:PMID:21267069], [cite:PMID:27864334]]. functions as a negative regulator of the innate immune system [[cite:PMID:17991829], [cite:PMID:22245969], [cite:PMID:23827681], [cite:PMID:33523931]]. This family also includes some viral sequences such as Putative ubiquitin thioesterase 232R from Invertebrate iridescent virus 3.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• OTUD1
• OTUD3
• OTUD4
• OTUD5
• OTUD6A
• OTUD6B