Seroatlas · Protein domains
DDB1- and CUL4-associated factor 8-like
IPR045151
Definition
This entry represents a group of WD and tetratricopeptide repeats proteins, including DCAF5/6/8 and DCAF8L1/DCAF8L2/WDTC1 from humans. They may function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex PMID:16964240. Proteins in this entry also include protein ALTERED SEED GERMINATION 2 (ASG2) from Arabidopsis. It is a negative regulator of ABA signalling PMID:26147561.
6 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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