Ionotropic glutamate receptor, L-glutamate and glycine-binding domain

Definition

This region, sometimes called the S1 domain, is the luminal domain just upstream of the first, M1, transmembrane region of transmembrane ion-channel proteins, and binds L-glutamate and glycine in the ionotropic glutamate receptor NMDA [[cite:PMID:10465381], [cite:PMID:8428958]]. It is found in association with [interpro:IPR001320].

18 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (18 proteins: gene, accession, name)

• GRIA1
• GRIA2
• GRIA3
• GRIA4
• GRID1
• GRID2
• GRIK1
• GRIK2
• GRIK3
• GRIK4
• GRIK5
• GRIN1
• GRIN2A
• GRIN2B
• GRIN2C
• GRIN2D
• GRIN3A
• GRIN3B