DNA-binding domain superfamily

Definition

This superfamily represents a DNA-binding domain with a 2-layer β(3)-α fold that is found in several DNA-binding proteins, including: DNA-binding domain of tn916 integrase PMID:9665166. N-terminal DNA-binding domain of lambda integrase PMID:15973401. GCC-box DNA-binding domains of certain transcription factors PMID:9736626. Methyl-CpG DNA-binding domain found in Methyl-CpG-binding protein 2 (MECP2) PMID:10518942 and methylation-dependent transcriptional repressor MBD1/PCM1 PMID:11371345.

11 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (11 proteins: gene, accession, name)

• BAZ2A
• BAZ2B
• MBD1
• MBD2
• MBD3
• MBD4
• MBD5
• MBD6
• MECP2
• SETDB1
• SETDB2