Putative DNA-binding domain superfamily
IPR009061
Definition
A putative DNA-binding domain with a conserved structure is found in several different protein families. The core structure of the domain consists of a three-helical fold that is architecturally similar to that of the "winged-helix" fold, but is topologically distinct. Representatives of this domain can be found in domains B1 and B5 from the beta subunit of phenylalanine-tRNA synthetases PMID:11679717, the C-terminal region of the DNA/RPA-binding domain of the DNA excision repair factor XPA PMID:10563794, the N-terminal domain of the transcriptional activators BmrR and MtaN PMID:11201751, the most conserved domain of the retinal development protein Dachshund PMID:12057194, and the DNA-binding domain of the gpNU1 subunit from the bacteriophage lambda viral packing protein terminase PMID:12049735.
10 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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