Elp3/MiaA/NifB-like, radical SAM core domain

Definition

This domain is found in FeMo cofactor biosynthesis protein NifB, PqqA peptide cyclase, Oxygen-independent coproporphyrinogen III oxidase (HemN), biotin synthase (BioB), Lipoyl synthase (LipA), Ribosomal protein S12 methylthiotransferase RimO, GTP 3',8-cyclase (MoaA) and tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase (MiaB), and similar proteins found in cellular organisms. This group includes a representative in the eukaryotic elongator subunit, Elp-3. Some members of this entry are methyltransferases [[cite:PMID:11222759], [cite:PMID:24476342]].

7 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (7 proteins: gene, accession, name)

• CDK5RAP1
• CDKAL1
• ELP3
• LIAS
• MOCS1
• RSAD1
• RSAD2