Seroatlas · Protein domains
Heat shock chaperonin-binding
IPR006636
Definition
This entry represents a heat shock chaperonin-binding domain found in human Stress-inducible phosphoprotein STI1 and similar sequences found in eukaryotes. STI1 acts as a co-chaperone for HSP90AA1 PMID:27353360. Both N- and C-terminal ends of STI1 are capable of binding heat shock proteins PMID:8999875. This domain is found both singly and duplicated in different proteins. This domain shows an α-helical structure PMID:34937942.
10 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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