Furin-like repeat

Definition

The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation [[cite:PMID:1936959], [cite:PMID:23756652], [cite:PMID:25480784]].

18 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (18 proteins: gene, accession, name)

• CRELD1
• CRELD2
• EGFR
• ERBB2
• ERBB3
• ERBB4
• FRAS1
• FURIN
• IGF1R
• INSR
• INSRR
• PCSK4
• PCSK5
• PCSK6
• RSPO1
• RSPO2
• RSPO3
• RSPO4