Seroatlas · Protein domains
SAPAP family
IPR005026
Definition
This entry represents the SAPAP family, whose members include mars from fruit flies and disks large-associated proteins from vertebrates. Mars binds to microtubules and protein phosphatase 1. It is involved in cell signalling, mitotic spindle organisation and regulation of mitotic cell cycle [[cite:PMID:23593258], [cite:PMID:17007873]]. It is essential for the early development of Drosophila embryos PMID:23593258.
5 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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