Seroatlas · Protein domains
Smooth muscle protein/calponin
IPR003096
Definition
Calponin is a smooth muscle-specific, actin-, tropomyosin- and calmodulin-binding protein believed to be involved in regulation or modulation of contraction PMID:8370452; interaction of the protein with actin inhibits actomyosin MgATPase activity. Multiple isoforms are found in smooth muscle PMID:8144658. Calponin is a basic protein of ~34 Kd PMID:8550594. The protein contains three repeats of a well-conserved 26-residue domain (see [interpro:IPR000557]).
11 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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