WAHD domain of WASH complex

Definition

This domain forms part of the WASH-complex of domains and proteins that activates the Arp2/3 complex, see [pfam:PF04062]. The Arp2/3 complex regulates endocytosis, sorting, and trafficking within the cell. The WAHD domain attaches to the FAM21 proteins via its N-terminal residues and to the microtubules via its C-terminal residues.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• WASH2P
• WASH3P
• WASH4P
• WASH6P
• WASHC1