Gasdermin pore forming domain

Definition

The precise function of this protein is unknown. A deletion/insertion mutation is associated with an autosomal dominant non-syndromic hearing impairment form PMID:9771715. In addition, this protein has also been found to contribute to acquired etoposide resistance in melanoma cells PMID:11297734. This family also includes the gasdermin protein PMID:10967128

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• GSDMA
• GSDMB
• GSDMC
• GSDMD
• GSDME
• PJVK