Seroatlas · Protein domains
Intercellular adhesion molecule (ICAM), N-terminal domain
PF03921
Definition
ICAMs normally functions to promote intercellular adhesion and signalling. However, The N-terminal domain of the receptor binds to the rhinovirus 'canyon' surrounding the icosahedral 5-fold axes, during the viral attachment process PMID:10562537. This family is a family that is part of the Ig superfamily and is therefore related to the family ig ([pfam:PF00047]).
5 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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