Seroatlas · Protein domains
Eukaryotic aspartyl protease
PF00026
Definition
Aspartyl (acid) proteases include pepsins, cathepsins, and renins. Two-domain structure, probably arising from ancestral duplication. This family does not include the retroviral nor retrotransposon proteases ([pfam:PF00077]), which are much smaller and appear to be homologous to a single domain of the eukaryotic asp proteases.
10 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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