Peptidase M14 domain-containing protein
IPR050753
Definition
This family of proteins includes enzymes that are primarily involved in the post-translational modification of proteins and peptides. They function as carboxypeptidases, which means they cleave C-terminal amino acids from proteins and peptides. Members of this family are involved in various biological processes, such as the regulation of peptide hormone and growth factor activity, modulation of the Wnt signaling pathway, and the processing of prohormones. They play roles in cellular interactions, inflammation, and the immune response by regulating the activity of vasoactive and inflammatory peptides. Some members also have roles in the extracellular matrix organization and may act as transcriptional repressors.
8 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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