Translation factor GTPase superfamily members

Definition

This family of proteins includes GTPases involved in various cellular processes, such as translation elongation, where they bind aminoacyl-tRNA to ribosomes, and translation termination, where they interact with release factors to mediate the end of protein synthesis. Some members are involved in the recognition and disassembly of stalled ribosomes, triggering mRNA decay pathways. Others participate in sulfur assimilation by catalyzing the adenylation of sulfate to produce adenosine 5'-phosphosulfate. They are part of the TRAFAC class translation factor GTPase superfamily and exhibit diverse functions across different biological contexts.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• EEF1A1
• EEF1A1P5
• EEF1A2
• GSPT1
• GSPT2
• HBS1L