EEF1A1P5
Putative elongation factor 1-alpha-like 3
Also known as: EF1A3_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for EEF1A1P5 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
462 residues, UniProt reviewed canonical sequence.
>Q5VTE0|EEF1A1P5
1 MGKEKTHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAAEMG KGSFKYAWVL
61 DKLKAERERG ITIDISLWKF ETSKYYVTII DAPGHRDFIK NMITGTSQAD CAVLIVAAGV
121 GEFEAGISKN GQTREHALLA YTLGVKQLIV GVNKMDSTEP PYSQKRYEEI VKEVSTYIKK
181 IGYNPDTVAF VPISGWNGDN MLEPSANMPW FKGWKVTRKD GNASGTTLLE ALDCILPPTR
241 PTDKPLRLPL QDVYKIGGIG TVPVGRVETG VLKPGMVVTF APVNVTTEVK SVEMHHEALS
301 EALPGDNVGF KVKNVSVKDV RRGNVAGDSK NDPPMEAAGF TAQVIILNHP GQISAGYAPV
361 LDCHMAHIAC KFAELKEKID RRSGKKLEDG PKFLKSGDAA IVDMVPGKPM CVESFSDYPP
421 LGRFAVRDMR QTVAVGVIKA VDKKAAGAGK VTKSAQKAQK AKLocalizationUniProt · AlphaFold · HPA
Whether an antibody against EEF1A1P5 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Intracellular
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.23
OntologyGO
Biological processes
Molecular functions
Cellular components
Protein domainsUniProt · Pfam · InterPro
- Translational (tr)-type GTP-binding domain
- Translation elongation factor EFTu-like, domain 2
- Translation elongation factor EF1A, eukaryotic/archaeal
- Translation protein, beta-barrel domain superfamily
- Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
- P-loop containing nucleoside triphosphate hydrolase
- Tr-type G domain, conserved site
- Translation factor GTPase superfamily members
- GTP-eEF1A, C-terminal domain
- Elongation factor Tu GTP binding domain
- Elongation factor Tu domain 2
- GTP-eEF1A C-terminal domain-like
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads EEF1A1P5 as an antibody target. Whether an autoantibody or antibody against EEF1A1P5 could matter depends on whether native EEF1A1P5 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
EEF1A1P5 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label EEF1A1P5 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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