Exocyst complex component EXOC3/Sec6, C-terminal domain

Definition

Sec6 is a component of the multiprotein exocyst complex. Sec6 interacts with Sec8, Sec10 and Exo70. These exocyst proteins localise to regions of active exocytosis-at the growing ends of interphase cells and in the medial region of cells undergoing cytokinesis-in an F-actin-dependent and exocytosis-independent manner PMID:11854409. This superfamily represents the C-terminal domain found in EXOC3/Sec6. Structurally, this domain consists of multiple helical bundles PMID:16699513.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• EXOC3
• EXOC3L1
• EXOC3L2
• EXOC3L4
• TNFAIP2