GAR domain superfamily

Definition

The GAR (Gas2-related) domain is common in plakin family members and Gas2 family members. It has been shown to bind to microtubules [[cite:PMID:20335501], [cite:PMID:11112700], [cite:PMID:11854008]] probably through the flexible, positively charged central β-sheet formed by by five antiparallel β-strands PMID:28541346. This domain has an α-β(5)-α fold with two layers (α/β) consisting of meander antiparallel sheet.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• DST
• GAS2
• GAS2L1
• GAS2L2
• GAS2L3
• MACF1