Galactosyltransferase, N-terminal

Definition

This entry represents the N-terminal domain in a family of galactosyltransferases. Galactosyltransferases possess up to three related galactosyltransferase activities, which in some cases are all catalysed by a single polypeptide: N-acetyllactosamine synthase ([ec:2.4.1.90]), β-N-acetylglucosaminyl-glycopeptide β-1,4-galactosyltransferase ([ec:2.4.1.38]) and lactose synthase (EC 2.4.1.22). In the absence of α-lactalbumin, the N-acetyllactosamine synthase reaction ([ec:2.4.1.90]) is catalysed; however, when α-lactalbumin is present, it forms the lactose synthase complex [[cite:PMID:9435216], [cite:PMID:9792633]]. Proteins containing this domain include β-1,4-galactosyltransferases and N-acetylgalactosaminyltransferases.

7 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (7 proteins: gene, accession, name)

• B4GALT1
• B4GALT2
• B4GALT3
• B4GALT4
• B4GALT5
• B4GALT6
• B4GALT7