Peptidase S1A, HAT/DESC1

Definition

This entry represents the type II transmembrane serine proteases (TTSPs), which belong to MEROPS peptidase family S1A (clan PA(S)). They include the HAT/DEASC1-like (human airway trypsin-like protease/ differentially expressed in squamous cell carcinoma gene 1) serine peptidases. They are activated by cleavage and secreted PMID:17388811. The entry includes the adrenal secretory serine peptidases, which are HAT peptidases that play an important role in airway physiology PMID:20620066.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• TMPRSS11A
• TMPRSS11B
• TMPRSS11D
• TMPRSS11E
• TMPRSS11F