Perilipin
IPR004279
Definition
The perilipin family includes lipid droplet-associated protein (perilipin) and adipose differentiation-related protein (adipophilin). Perilipin is a modulator of adipocyte lipid metabolism and adipophilinis are involved in the development and maintenance of adipose tissue. The relative expression of these proteins and protective nature of lipid droplets from lipase activity depends on the balance of lipid storage and utilisation in specific cells [[cite:PMID:26357594], [cite:PMID:28754637]]. TIP47, also known as perilipin-3, is a cargo selection device for mannose 6-phosphate receptor trafficking that is also included in this group [[cite:PMID:9590177], [cite:PMID:15242596]].
5 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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