Seroatlas · Protein domains
GAR domain
IPR003108
Definition
The GAR (Gas2-related) domain is common in plakin family members and Gas2 family members. It has been shown to bind to microtubules [[cite:PMID:20335501], [cite:PMID:11112700], [cite:PMID:11854008]] probably through the flexible, positively charged central β-sheet formed by by five antiparallel β-strands PMID:28541346.
6 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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