Seroatlas · Human Serome Atlas

SUMO1P1

Small ubiquitin-related modifier 5

Also known as: SUMO5_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: G2XKQ0
Gene: SUMO1P1
Canonical length: 101 aa

OverviewNCBI Gene

No narrative summary is available for SUMO1P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

101 residues, UniProt reviewed canonical sequence.

>G2XKQ0|SUMO1P1
     1  MSDLEAKPST EHLGDKIKDE DIKLRVIGQD SSEIHFKVKM TTPLKKLKKS YCQRQGVPVN
    61  SLRFLFEGQR IADNHTPEEL GMEEEDVIEV YQEQIGGHST V

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SUMO1P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.42

OntologyGO

Biological processes

Molecular functions

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

InteractionsUniProt · HPA

Protein binding partners of SUMO1P1 in the human serome: UniProt-annotated complex subunits plus reported interactors. Each links to its own Seroatlas record.

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SUMO1P1 as an antibody target. Whether an autoantibody or antibody against SUMO1P1 could matter depends on whether native SUMO1P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SUMO1P1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SUMO1P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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