Seroatlas · Human Serome Atlas

MAGEA13P

Putative MAGE domain-containing protein MAGEA13P

Also known as: MA13P_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NCF6
Gene: MAGEA13P
Canonical length: 341 aa

OverviewNCBI Gene

No narrative summary is available for MAGEA13P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

341 residues, UniProt reviewed canonical sequence.

>A6NCF6|MAGEA13P
     1  MPHSQKSRHC ELEQGLQAPK EAQGLVGVQV AEAEKVNTTA SSSPSTLIQG TLEKVSASGT
    61  PGTPQSSQRV CSPCTTIKAT PWNQSDESSR SQEKKDPGAS QALMLEKKVD ELVKFLSVKY
   121  TTKQPITEAE MLKGVIKEHK DHFPPIFMQA HECMEIVFGT DMKEVDPISH SCVLLKSLDL
   181  TYDRRLSDDQ GMPKTGLLIL TFGVILMEAN CASEEKIWEV LNIIRVYAGW KDFIYGEPRK
   241  LITRDLVQEK YLECCQVSNS DPPRYKFPWG PRAHAETTKM KVLEFFSRVS GSDASSFPLL
   301  YEEALRDEKE KAQAIIATMG GTTLMASAHS WAKSSSFSCP E

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against MAGEA13P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.43

OntologyGO

Biological processes

negative regulation of transcription by RNA polymerase II

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads MAGEA13P as an antibody target. Whether an autoantibody or antibody against MAGEA13P could matter depends on whether native MAGEA13P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

MAGEA13P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label MAGEA13P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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