Seroatlas · Human Serome Atlas

CTBP1-DT

DNA damage up-regulated protein

Also known as: DDUP_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: C0HM98
Gene: CTBP1-DT
Canonical length: 186 aa

OverviewNCBI Gene

No narrative summary is available for CTBP1-DT in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

186 residues, UniProt reviewed canonical sequence.

>C0HM98|CTBP1-DT
     1  MWLVECTGRD LTGLSCLLSM DRQPRRRQHV AGCRDVPPPL PQGSWGQTSP RHSILCSKSG
    61  CDLLGGGEYN GETSGEEFLA PAWTCRAQQA ATWLSVQQTS HKALGPAGGA AMSSKLSPEE
   121  QFLSRIHFLR TFMCSVAGAE LPGIPQATEN GEGCRPARDP ASSPSSLSMA SVYTQCSSAQ
   181  LVSALS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against CTBP1-DT can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.5

OntologyGO

Biological processes

Cellular components

KeywordsUniProt

InteractionsUniProt · HPA

Protein binding partners of CTBP1-DT in the human serome: UniProt-annotated complex subunits plus reported interactors. Each links to its own Seroatlas record.

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads CTBP1-DT as an antibody target. Whether an autoantibody or antibody against CTBP1-DT could matter depends on whether native CTBP1-DT is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

CTBP1-DT is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label CTBP1-DT as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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