Exportin 1-like protein

Definition

The sequences featured in this family are similar to a region close to the N-terminus of yeast exportin 1 (Xpo1, Crm1, [swissprot:P14068]). This region is found just C-terminal to an importin-beta N-terminal domain ([pfam:PF03810]) in many members of this family. Exportin 1 is a nuclear export receptor that interacts with leucine-rich nuclear export signal (NES) sequences, and Ran-GTP, and is involved in translocation of proteins out of the nucleus [[cite:PMID:9323132],[cite:PMID:9323123]].

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• IPO13
• TNPO3
• XPO1
• XPO5
• XPO6
• XPOT