Seroatlas · Protein domains
Complex 1 protein (LYR family)
PF05347
Definition
Proteins in this family include an accessory subunit of the higher eukaryotic NADH dehydrogenase complex. In Saccharomyces cerevisiae, the Isd11 protein ([swissprot:Q6Q560]) has been shown to play a role in Fe/S cluster biogenesis in mitochondria PMID:16341090PMID:16341089. We have named this family LYR after a highly conserved tripeptide motif close to the N-terminus of these proteins.
8 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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