Heterogeneous nuclear ribonucleoprotein L, RRM domain

Definition

This entry represents the fourth RRM domain found at the C-terminal of human Heterogeneous nuclear ribonucleoprotein L (HNRNPL) PMID:26051023, an splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion [[cite:PMID:11809897], [cite:PMID:22570490], [cite:PMID:24164894], [cite:PMID:25623890], [cite:PMID:33174841]]. It is also found in the Polypyrimidine tract-binding protein 1/2/3 that play a role in pre-mRNA splicing and in the regulation of alternative splicing events.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• HNRNPL
• HNRNPLL
• PTBP1
• PTBP2
• PTBP3