Adapter and Engulfment Domain-Containing Protein

Definition

This family of proteins includes various adapter proteins that play roles in cellular processes such as endocytosis, nitric oxide synthesis regulation, and phagocytosis of apoptotic cells. Members of this family are involved in the formation of protein complexes that are essential for specific functions at the cellular level, including synaptic functions and cellular transport. Some proteins in this family mediate interactions between enzymes and regulatory proteins, enhancing their activities. Others are involved in the internalization and trafficking of receptors and their ligands, contributing to cellular signaling and uptake of nutrients. The family also includes proteins that are necessary for the clearance of cellular debris and the restructuring of the cytoskeleton during developmental processes.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• FAM43A
• FAM43B
• GULP1
• LDLRAP1
• NOS1AP