Major Intrinsic Protein/Aquaporin
IPR050363
Definition
The MIP/aquaporin family is a group of membrane proteins that facilitate the transport of water and small solutes across cell membranes. Members of this family are characterized by their ability to form channels that selectively allow the passage of water, glycerol, urea, and other small, non-charged molecules. These proteins are involved in various physiological processes, including osmoregulation, skin hydration, wound healing, and energy homeostasis. Aquaporins play a crucial role in maintaining water balance in cells and are found in a wide range of organisms, from bacteria to humans. Some family members also participate in the transport of gases like carbon dioxide and ammonia, contributing to processes such as nitrogen support in symbiotic relationships and gas exchange.
5 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
Loading the interactive Seroatlas explorer...