Replication factor C, lid domain

Definition

Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA superfamily and consist of a ATPase domain, a lid domain and a C-terminal domain [[cite:PMID:24436332], [cite:PMID:26918303], [cite:PMID:15037234], [cite:PMID:22520345], [cite:PMID:22918590], [cite:PMID:23545418]]. This entry represents the lid domain.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• CHTF18
• RFC1
• RFC2
• RFC4
• RFC5