Ski-like, DNA-binding domain superfamily

Definition

The c-ski proto-oncogene has been shown to influence proliferation, morphological transformation and myogenic differentiation PMID:7999783. It may play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Sno, a Ski proto-oncogene homologue, is expressed in two isoforms and plays a role in the response to proliferation stimuli. Ski is a multidomain protein that includes a domain bearing high sequence similarity with the retinal determination protein Dachshund PMID:15130471. This conserved domain contains a DNA binding motif PMID:12057194.

7 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (7 proteins: gene, accession, name)

• DACH1
• DACH2
• SKI
• SKIDA1
• SKIL
• SKOR1
• SKOR2