Protein-arginine deiminase, central domain superfamily

Definition

Peptidylarginine deiminase (PAD) enzymes catalyse the conversion of protein-bound arginine to citrulline. There are five types of PADs known in humans, PAD1-PAD4 and PAD6 PMID:14579251. PAD6 does not bind Ca2+ and is inactive in vitro assays against standard PADs substrate PMID:39286527. This entry represents the central non-catalytic domain of protein-arginine deiminase. This domain has an immunoglobulin-like fold PMID:16567635.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• PADI1
• PADI2
• PADI3
• PADI4
• PADI6